Hydrochloric Acid → 2-amino-4-[5-(3,5-dichlorophenyl)-5-trifiuoromethyl-4,5-dihydroisoxazol-3-yl]-N-(2,2,2-trifiuoroethyl) benzoic acid amide

HRID 2337427Notes

Reaction equation

HRID 2337427 reaction equation
[CH2:35]([N:36]([CH2:37][CH3:38])[CH2:39][CH2:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH3:46])[CH3:47].[CH3:52][N:53]([c:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1)[CH3:60].[CH:48]([Cl:49])([Cl:50])[Cl:51].[ClH:34].[F:28][C:29]([CH2:30][NH2:31])([F:32])[F:33].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([C:11]2=[N:12][O:13][C:14]([C:16]([F:17])([F:18])[F:19])([c:20]3[cH:21][c:22]([Cl:27])[cH:23][c:24]([Cl:26])[cH:25]3)[CH2:15]2)[cH:10]1>>[NH2:1][c:2]1[c:3]([C:4](=[O:6])[NH:31][CH2:30][C:29]([F:28])([F:32])[F:33])[cH:7][cH:8][c:9]([C:11]2=[N:12][O:13][C:14]([C:16]([F:17])([F:18])[F:19])([c:20]3[cH:21][c:22]([Cl:27])[cH:23][c:24]([Cl:26])[cH:25]3)[CH2:15]2)[cH:10]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6212ChloroformHCID 9773Ethanamine, 2,2,2-trifluoro-HCID 142844-(Dimethylamino)pyridineHCID 99645131-Ethyl-3-(3-diethylaminopropyl)carbodiimideHCID 667838402-Amino-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]benzoic acid

Product 1

HCID 866114682-amino-4-[5-(3,5-dichlorophenyl)-5-trifiuoromethyl-4,5-dihydroisoxazol-3-yl]-N-(2,2,2-trifiuoroethyl) benzoic acid amide

Sources & evidence

ORD record
ord-03a1d37586c64ce099fd6250e83a2e9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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