Diethyl Ether → Ethyl 6-hydroxy-6-(3-pyridinyl)-3-azabicyclo[3.2.1]octane-3-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[O:20]=[C:21]1[CH:22]2[CH2:23][N:24]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:25][CH:26]([CH2:27]1)[CH2:28]2.[n:13]1[cH:14][cH:15][cH:16][cH:17][c:18]1[Li:19]>>[c:2]1([C:21]2([OH:20])[CH:22]3[CH2:23][N:24]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:25][CH:26]([CH2:27]2)[CH2:28]3)[cH:3][n:4][cH:5][cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-817d3aeed34d4b50b7440727c4601f46
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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