Hydrochloric Acid → (4-Tert-butyl-benzyl)-[2-(4-fluoro-3-trifluoromethyl-phenyl)-ethyl]-amine

HRID 2337765Notes

Reaction equation

HRID 2337765 reaction equation
[BH4-:34].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH:9]=[O:10])[cH:11][cH:12]1.[C:28](=[O:29])([O-:30])[O-:31].[CH3:37][OH:38].[ClH:13].[ClH:36].[F:14][c:15]1[c:16]([C:24]([F:25])([F:26])[F:27])[cH:17][c:18]([CH2:21][CH2:22][NH2:23])[cH:19][cH:20]1.[K+:32].[K+:33].[Na+:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][NH:23][CH2:22][CH2:21][c:18]2[cH:17][c:16]([C:24]([F:25])([F:26])[F:27])[c:15]([F:14])[cH:20][cH:19]2)[cH:11][cH:12]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 813Potassium Cation2×HCID 887MethanolHCID 923Sodium ionHCID 19660Carbonate IonHCID 28123BorohydrideHCID 703244-tert-ButylbenzaldehydeHCID 18543298HCID 18543298, compound

Product 1

HCID 68563599(4-Tert-butyl-benzyl)-[2-(4-fluoro-3-trifluoromethyl-phenyl)-ethyl]-amine

Sources & evidence

ORD record
ord-031a2fb1a10543bea8a4c51f384c13c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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