Dimethylformamide → (1-{2-[5-(4-bromo-naphthalen-1-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

HRID 2338221Notes

Reaction equation

HRID 2338221 reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[N:8]1[CH:9]([c:13]2[nH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([Br:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1)[CH3:7].[CH3:29][O:30][C:31](=[O:32])[NH:33][CH:34]([C:35]([OH:36])=[O:37])[CH:38]([CH3:39])[CH3:40].[CH3:65][N:66]1[CH2:67][CH2:68][O:69][CH2:70][CH2:71]1.[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[P-:41]([F:42])([F:43])([F:44])([F:45])([F:46])[F:47].[n:48]1([O:49][C:50]([N:51]([CH3:52])[CH3:53])=[N+:54]([CH3:55])[CH3:56])[c:57]2[n:58][cH:59][cH:60][cH:61][c:62]2[n:63][n:64]1>>[O:5]=[C:6]([N:8]1[CH:9]([c:13]2[nH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([Br:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1)[CH:34]([NH:33][C:31]([O:30][CH3:29])=[O:32])[CH:38]([CH3:39])[CH3:40]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 138211012-((Methoxycarbonyl)amino)-3-methylbutanoic acidHCID 666204542-[5-(4-Bromo-naphthalen-1-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 66620068(1-{2-[5-(4-bromo-naphthalen-1-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Sources & evidence

ORD record
ord-817cd45742744a38a58ef12239fd52dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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