Tetrahydrofuran → (4-((((1,1-Dimethylethyl)(dimethyl)silyl)oxy)methyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-2-yl)methanol
Reaction equation
[Al+3:30].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:1][C:2]([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]([C:23](=[O:24])[O:25][CH3:26])[c:11](-[c:14]2[c:15]([F:22])[cH:16][cH:17][c:18]([O:20][CH3:21])[cH:19]2)[cH:12][cH:13]1)([CH3:27])[CH3:28].[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31]>>[CH3:1][C:2]([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]([CH2:23][OH:24])[c:11](-[c:14]2[c:15]([F:22])[cH:16][cH:17][c:18]([O:20][CH3:21])[cH:19]2)[cH:12][cH:13]1)([CH3:27])[CH3:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7df3f42ccf9245729a01b8a5d6a756bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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