Sodium ion → N-[5-chloro-7-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Reaction equation
[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:62][CH2:63][O:64][CH2:65][CH3:66].[Cl:16][c:17]1[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][CH2:32][N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[c:24]([O:27][CH3:28])[cH:25][c:26]12.[Cl:39][c:40]1[c:41]([NH2:56])[c:42]2[c:43]([c:47]([C:49]#[C:50][C:51]([CH3:52])([CH3:53])[O:54][CH3:55])[cH:48]1)[O:44][CH2:45][O:46]2.[Na+:10].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1.[O:57]=[CH:58][N:59]([CH3:60])[CH3:61]>>[c:17]1([NH:56][c:41]2[c:40]([Cl:39])[cH:48][c:47]([C:49]#[C:50][C:51]([CH3:52])([CH3:53])[O:54][CH3:55])[c:43]3[c:42]2[O:46][CH2:45][O:44]3)[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][CH2:32][N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[c:24]([O:27][CH3:28])[cH:25][c:26]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-6621204741eb464e80236b28ac9a8f0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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