Dimethylformamide → N-[[4-methoxy-2-(trifluoromethyl)phenyl]methyl]-3-[[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino]cyclohexane-1-carboxamide

HRID 2339600Notes

Reaction equation

HRID 2339600 reaction equation
[CH3:1][c:2]1[n:3][c:4]([NH:10][CH:11]2[CH2:12][CH:13]([C:17](=[O:18])[OH:19])[CH2:14][CH2:15][CH2:16]2)[n:5][c:6]([NH:8][CH3:9])[n:7]1.[CH3:20][O:21][c:22]1[cH:23][c:24]([C:30]([F:31])([F:32])[F:33])[c:25]([CH2:28][NH2:29])[cH:26][cH:27]1.[CH3:70][N:71]([CH3:72])[CH:73]=[O:74].[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[P-:43]([F:44])([F:45])([F:46])([F:47])([F:48])[F:49].[n:50]1([O:51][P+:52]([N:53]([CH3:54])[CH3:55])([N:56]([CH3:57])[CH3:58])[N:59]([CH3:60])[CH3:61])[c:62]2[cH:63][cH:64][cH:65][cH:66][c:67]2[n:68][n:69]1>>[CH3:1][c:2]1[n:3][c:4]([NH:10][CH:11]2[CH2:12][CH:13]([C:17](=[O:19])[NH:29][CH2:28][c:25]3[c:24]([C:30]([F:31])([F:32])[F:33])[cH:23][c:22]([O:21][CH3:20])[cH:27][cH:26]3)[CH2:14][CH2:15][CH2:16]2)[n:5][c:6]([NH:8][CH3:9])[n:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 124335Benzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 43138648[4-Methoxy-2-(trifluoromethyl)phenyl]methanamineHCID 594482213-{[4-Methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxylic acid

Product 1

HCID 67493512N-[[4-methoxy-2-(trifluoromethyl)phenyl]methyl]-3-[[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino]cyclohexane-1-carboxamide

Sources & evidence

ORD record
ord-ae4b40740a2840a88d9440c504050d6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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