Hydrochloric Acid → 5-chloro-6-methoxy-1-[1-(tetrahydro-2H-pyran-4-yl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Reaction equation
[C:28]([BH3-:29])#[N:30].[CH3:2][O:3][c:4]1[c:5]([Cl:20])[cH:6][c:7]2[c:8]([n:9]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[c:10](=[O:12])[nH:11]2)[cH:19]1.[CH3:32][OH:33].[ClH:1].[Na+:31].[O:21]1[CH2:22][CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1>>[CH3:2][O:3][c:4]1[c:5]([Cl:20])[cH:6][c:7]2[c:8]([n:9]([CH:13]3[CH2:14][CH2:15][N:16]([CH:24]4[CH2:23][CH2:22][O:21][CH2:26][CH2:25]4)[CH2:17][CH2:18]3)[c:10](=[O:12])[nH:11]2)[cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-133af88c2bb44fd9acd20d19c8414d63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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