Acetic Acid → 5-Bromo-2-fluoropyridin-3-ol

HRID 2339931Notes

Reaction equation

HRID 2339931 reaction equation
[Br:1][c:2]1[cH:3][c:4]([B:9]([OH:10])[OH:11])[c:5]([F:8])[n:6][cH:7]1.[CH3:12][C:13]([OH:14])=[O:15].[CH3:16][CH2:17][O:18][C:19](=[O:20])[CH3:21].[CH3:24][CH2:25][OH:26].[OH:22][OH:23]>>[Br:1][c:2]1[cH:3][c:4]([OH:14])[c:5]([F:8])[n:6][cH:7]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 702EthanolHCID 784Hydrogen PeroxideHCID 8857Ethyl AcetateHCID 27832425-Bromo-2-fluoropyridine-3-boronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 201118655-Bromo-2-fluoropyridin-3-ol

Sources & evidence

ORD record
ord-e3eedbd83afb4fcbb36b213e9a8e17ba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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