Ethylene Glycol → [1-(6-Chloropyridin-3-yl)-pyrrolidin-3-yl]-(2,4-dichlorobenzyl)-amine
Reaction equation
[C:9](=[O:10])([O-:11])[O-:12].[CH:34]([OH:35])([CH3:36])[CH3:37].[Cl:15][c:16]1[c:17]([CH2:18][NH:19][CH:20]2[CH2:21][NH:22][CH2:23][CH2:24]2)[cH:25][cH:26][c:27]([Cl:29])[cH:28]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([I:8])[cH:6][cH:7]1.[Cu:38]([I:39])[I:40].[K+:13].[K+:14].[OH:30][CH2:31][CH2:32][OH:33]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([N:22]2[CH2:21][CH:20]([NH:19][CH2:18][c:17]3[c:16]([Cl:15])[cH:28][c:27]([Cl:29])[cH:26][cH:25]3)[CH2:24][CH2:23]2)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-486c176b998341e793a200834e7cd972
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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