Hydrochloric Acid → tert-Butyl 2-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate
Reaction equation
[BH4-:34].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:37][OH:38].[ClH:36].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[s:13]3)[cH:27][cH:28][c:29]([N+:31]([O-:32])=[O:33])[cH:30]1.[Na+:35].[Ni:44]([Cl:45])[Cl:46]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[s:13]3)[cH:27][cH:28][c:29]([NH2:31])[cH:30]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-39b5a62ff7ae4224a3e705cdbbc204ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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