Triethylamine → 7,8-difluoro-3-methyl-2H-1,4-benzoxazine

HRID 2341809Notes

Reaction equation

HRID 2341809 reaction equation
[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[Cl:1][O:2][C:3]([CH3:4])([CH3:5])[CH3:6].[F:7][c:8]1[c:9]([F:19])[c:10]2[c:11]([cH:17][cH:18]1)[NH:12][CH:13]([CH3:16])[CH2:14][O:15]2>>[F:7][c:8]1[c:9]([F:19])[c:10]2[c:11]([cH:17][cH:18]1)[N:12]=[C:13]([CH3:16])[CH2:14][O:15]2

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 521297Tert-Butyl hypochloriteHCID 102197187,8-Difluoro-2,3-dihydro-3-methyl-4H-(1,4)benzoxazine

Product 1

HCID 109431177,8-difluoro-3-methyl-2H-1,4-benzoxazine

Sources & evidence

ORD record
ord-2f89b15d0cee4b63a6477c52a7816ff4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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