Acetonitrile → 5-Chloro-4-methylindolin-2-one

HRID 2342245Notes

Reaction equation

HRID 2342245 reaction equation
[CH3:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[NH:6][C:5](=[O:11])[CH2:4]2.[CH3:27][C:28]#[N:29].[Cl:12][N:13]1[C:14](=[O:15])[CH2:16][CH2:17][C:18]1=[O:19].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[CH3:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][c:10]1[Cl:12])[NH:6][C:5](=[O:11])[CH2:4]2

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 6422Trifluoroacetic acidHCID 31398ChlorosuccinimideHCID 125793824-Methyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 103133885-Chloro-4-methylindolin-2-one

Sources & evidence

ORD record
ord-a4ef5ef3cfd94d679e426079b4f38a30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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