Tetrahydrofuran → 4-tert-Butoxycarbonylamino-5-(1-trityl-1H-imidazol-4-yl)-pent-2-enoic acid ethyl ester

HRID 2342566Notes

Reaction equation

HRID 2342566 reaction equation
[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31]([NH:32][CH:33]([CH2:34][c:35]1[n:36][cH:37][n:38]([C:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:39]1)[CH:59]=[O:60])=[O:61].[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[CH:20][C:21](=[O:22])[O:23][CH2:24][CH3:25])[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH:20]([C:21](=[O:22])[O:23][CH2:24][CH3:25])=[CH:62][CH:33]([NH:32][C:31]([O:30][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:61])[CH2:34][c:35]1[n:36][cH:37][n:38]([C:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:39]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 70670Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl esterHCID 86591139[1-Formyl-2-(1-trityl-1H-imidazol-4-yl)-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 694162234-tert-Butoxycarbonylamino-5-(1-trityl-1H-imidazol-4-yl)-pent-2-enoic acid ethyl ester

Sources & evidence

ORD record
ord-bcf440f4899a4856b71b65277acab9a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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