1,2,4-Trichlorobenzene → 2-[4-(4-Methylbenzyl)-1-piperazinyl]-4-phenylpyridine

HRID 2342872Notes

Reaction equation

HRID 2342872 reaction equation
[CH3:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][N:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[cH:26][cH:27]1.[CH:28]([O:29][CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1.[Cl:35][c:36]1[cH:37][c:38]([Cl:39])[c:40]([Cl:41])[cH:42][cH:43]1>>[c:2]1([N:23]2[CH2:22][CH2:21][N:20]([CH2:19][c:18]3[cH:17][cH:16][c:15]([CH3:14])[cH:27][cH:26]3)[CH2:25][CH2:24]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1

Participants

5

Reactant 4

HCID 131,2,4-TrichlorobenzeneHCID 7914Diisopropyl EtherHCID 7647231-(4-Methylbenzyl)piperazineHCID 27628422-Chloro-4-phenylpyridine

Product 1

HCID 140994852-[4-(4-Methylbenzyl)-1-piperazinyl]-4-phenylpyridine

Sources & evidence

ORD record
ord-77f0b3546a5b4c1899812479bfddea3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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