Dimethylformamide → Tert-butyl 3-[[2-[4-fluoro-2-(4-methoxybutylamino)anilino]-2-oxoacetyl]-(2-methylpropyl)amino]-5-(morpholine-4-carbonyl)piperidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:22]([CH2:23][CH:24]([CH3:25])[CH3:26])[C:27]([C:28](=[O:29])[OH:30])=[O:31])[CH2:11][CH:12]([C:14](=[O:15])[N:16]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[CH2:13]1.[CH:57]([N:58]([CH:59]([CH3:60])[CH3:61])[CH2:62][CH3:63])([CH3:64])[CH3:65].[F:42][c:43]1[cH:44][c:45]([NH:50][CH2:51][CH2:52][CH2:53][CH2:54][O:55][CH3:56])[c:46]([NH2:47])[cH:48][cH:49]1.[O:66]=[CH:67][N:68]([CH3:69])[CH3:70].[OH:32][n:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[n:40][n:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:22]([CH2:23][CH:24]([CH3:25])[CH3:26])[C:27]([C:28](=[O:29])[NH:47][c:46]2[c:45]([NH:50][CH2:51][CH2:52][CH2:53][CH2:54][O:55][CH3:56])[cH:44][c:43]([F:42])[cH:49][cH:48]2)=[O:31])[CH2:11][CH:12]([C:14](=[O:15])[N:16]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a5c3be659fba4c2a906050fd9211dcf1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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