Pyridine → tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

HRID 2343613Notes

Reaction equation

HRID 2343613 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:6][cH:7]1.[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[OH:12][CH2:13][CH:14]1[N:15]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:16][CH2:17][CH2:18]1.[cH:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[O:12][CH2:13][CH:14]2[N:15]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:16][CH2:17][CH2:18]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 8857Ethyl AcetateHCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 13110388tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-e86c15f7be02457e91a18e7dc88236fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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