Sodium ion → N-tert-Butyloxycarbonyl-3-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline

HRID 2343945Notes

Reaction equation

HRID 2343945 reaction equation
[BH4-:54].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]2[CH2:16][CH:17]1[C:18](=[O:19])[OH:20].[CH2:56]1[O:57][CH2:58][CH2:59][CH2:60]1.[CH:45]([N:46]([CH2:47][CH3:48])[CH:49]([CH3:50])[CH3:51])([CH3:52])[CH3:53].[Na+:55].[P-:21]([F:22])([F:23])([F:24])([F:25])([F:26])[F:27].[n:28]1([O:29][C:30]([N:31]([CH3:32])[CH3:33])=[N+:34]([CH3:35])[CH3:36])[c:37]2[n:38][cH:39][cH:40][cH:41][c:42]2[n:43][n:44]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]2[CH2:16][CH:17]1[CH2:18][OH:19]

Participants

8

Reactant 7

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 9886HexafluorophosphateHCID 28123BorohydrideHCID 81531DiisopropylethylamineHCID 27356492-[(Tert-butoxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 12114559N-tert-Butyloxycarbonyl-3-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-76dc11612db7467394e7a8d6090c5d41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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