Sodium ion → 4-Amino-1-(2-chloropyrimidin-4-yl)-4-methylpiperidine

HRID 2344074Notes

Reaction equation

HRID 2344074 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][C:9]1([CH3:22])[CH2:10][CH2:11][N:12]([c:15]2[n:16][c:17]([Cl:21])[n:18][cH:19][cH:20]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[CH2:40]([Cl:41])[Cl:42].[CH3:23][O:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[Na+:39].[OH-:38].[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[NH2:8][C:9]1([CH3:22])[CH2:10][CH2:11][N:12]([c:15]2[n:16][c:17]([Cl:21])[n:18][cH:19][cH:20]2)[CH2:13][CH2:14]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 961HydroxideHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 19694924HCID 19694924, compound

Product 1

HCID 196949304-Amino-1-(2-chloropyrimidin-4-yl)-4-methylpiperidine

Sources & evidence

ORD record
ord-645b078f3774499e9f338d104e50128e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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