Potassium Carbonate → 1-Bromo-2-fluoro-4-tridecyloxybenzene

HRID 234552Notes

Reaction equation

HRID 234552 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].Br[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH3:11])=[CH:4][C:3]=1[F:9]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 130001-BromotridecaneHCID 27791534-Bromo-3-fluorophenol

Product 1

HCID 233547251-Bromo-2-fluoro-4-tridecyloxybenzene

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

This was prepared using a similar method to that described for compound 3. Quantities: compound 1 (4.02 g, 21.1 mmol), 1-bromotridecane (6.11 g, 23.2 mmol), potassium carbonate (5.22 g, 37.8 mmol) and butanone (115 ml).

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-b754ed3169634929b3e30f44e30db084
Source dataset
uspto-grants-1997_01
Patent number
US05595682

Reaction notes

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