Dimethylformamide → 3-Bromo-6-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-quinoline
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([O:12][S:13]([C:14]([F:15])([F:16])[F:17])(=[O:18])=[O:19])[cH:9][c:10]2[cH:11]1.[CH3:29][c:30]1[cH:31][cH:32][c:33]2[n:34]([n:35]1)[c:36]([SH:39])[n:37][n:38]2.[CH:20]([N:21]([CH:22]([CH3:23])[CH3:24])[CH2:25][CH3:26])([CH3:27])[CH3:28].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[O:47]=[C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1.[O:65]=[C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)[CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[O:83]=[C:84]([CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1)[CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1.[Pd:45].[Pd:46]>>[Br:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([S:39][c:36]3[n:34]4[c:33]([cH:32][cH:31][c:30]([CH3:29])[n:35]4)[n:38][n:37]3)[cH:9][c:10]2[cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4d52072bc26e47c098655368d12c5c3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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