Methanol → 5-Methoxy-7-iodo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one
Reaction equation
[CH3:25][OH:26].[CH3:27][O-:28].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[CH3:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46].[F:1][c:2]1[cH:3][c:4]2[c:8]([c:9]([I:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]1)[CH2:5]2.[Na+:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[c:2]1([O:30][CH3:31])[cH:3][c:4]2[c:8]([c:9]([I:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]1)[CH2:5]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ea76a8a2648d4173858c4136124c2e72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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