Triethylamine → 2,5-Difluoro-4-chloropyrimidine

HRID 2346172Notes

Reaction equation

HRID 2346172 reaction equation
[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[CH3:18][CH2:19][O:20][C:21](=[O:22])[CH3:23].[F:1][c:2]1[n:3][c:4]([Cl:10])[c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[F:1][c:2]1[n:3][c:4]([Cl:10])[c:5]([F:9])[cH:6][n:7]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 133889922,5-Difluoro-4,6-dichloropyrimidine

Product 1

HCID 137111632,5-Difluoro-4-chloropyrimidine

Sources & evidence

ORD record
ord-e88d63f39bfb4beaae563df6d628f726
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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