Toluene → N-{5-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophen-2-ylmethyl}-propionamide
Reaction equation
[CH2:38]([SiH:39]([CH2:40][CH3:41])[CH2:42][CH3:43])[CH3:44].[CH3:26][CH2:27][C:28]([NH2:29])=[O:30].[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:22]([F:23])([F:24])[F:25])[CH2:10][C:11]([c:14]3[cH:15][c:16]([CH3:21])[c:17]([CH:19]=[O:20])[s:18]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1.[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:22]([F:23])([F:24])[F:25])[CH2:10][C:11]([c:14]3[cH:15][c:16]([CH3:21])[c:17]([CH2:19][NH:29][C:28]([CH2:27][CH3:26])=[O:30])[s:18]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-06745f9e51074e56b04e6d92aa749793
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…