Tetrahydrofuran → DV-7028 hydrochloride

HRID 2346728Notes

Reaction equation

HRID 2346728 reaction equation
[F:13][c:14]1[cH:15][cH:16][c:17]([C:18](=[O:19])[CH:20]2[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][OH:28])[CH2:24][CH2:25]2)[cH:29][cH:30]1.[O:50]=[C:51]([O:52][CH2:53][CH3:54])[N:55]=[N:56][C:57]([O:58][CH2:59][CH3:60])=[O:61].[O:62]1[CH2:63][CH2:64][CH2:65][CH2:66]1.[c:31]1([P:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46][cH:47][cH:48][cH:49]1.[n:1]1[c:2]2[n:3]([c:4](=[O:8])[nH:5][c:6]1=[O:7])[CH2:9][CH2:10][CH2:11][CH2:12]2>>[n:1]1[c:2]2[n:3]([c:4](=[O:8])[n:5]([CH2:27][CH2:26][N:23]3[CH2:22][CH2:21][CH:20]([C:18]([c:17]4[cH:16][cH:15][c:14]([F:13])[cH:30][cH:29]4)=[O:19])[CH2:25][CH2:24]3)[c:6]1=[O:7])[CH2:9][CH2:10][CH2:11][CH2:12]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 148921654-(4-Fluorobenzoyl)-1-(2-hydroxyethyl)piperidineHCID 151053696,7,8,9-Tetrahydropyrido[1,2-a][1,3,5]triazine-2,4-dione

Product 1

HCID 131620DV-7028 hydrochloride

Sources & evidence

ORD record
ord-348431d1ae144d2a97a38d51e5de2e6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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