Hydrochloric Acid → 1-[2-(4-Trifluoromethyl-phenyl)-4-(4-trifluoromethyl-piperidin-1-ylmethyl)-thiazol-5-yl]-propan-1-ol
Reaction equation
[CH3:50][CH2:51][OH:52].[ClH:44].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][c:11]([CH:25]([CH2:26][CH3:27])[O:28][C:29](=[O:30])[CH:31]([O:32][CH3:33])[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[c:12]([CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([C:21]([F:22])([F:23])[F:24])[CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1)([F:40])[F:41].[Na+:43].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1.[OH-:42].[OH2:53]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][c:11]([CH:25]([CH2:26][CH3:27])[OH:28])[c:12]([CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([C:21]([F:22])([F:23])[F:24])[CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1)([F:40])[F:41]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-36dc670da5674c89b1cbc95aea979c8e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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