Dichloromethane → 10-[(2-Methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid methyl-[(2-oxo-[1,3]dioxolan-4-yl)methyl]-amide
Reaction equation
[C:52](=[O:53])([n:54]1[cH:55][cH:56][n:57][cH:58]1)[n:59]1[cH:60][cH:61][n:62][cH:63]1.[CH:43]([N:44]([CH2:45][CH3:46])[CH:47]([CH3:48])[CH3:49])([CH3:50])[CH3:51].[Cl:64][CH2:65][Cl:66].[OH:1][CH:2]([CH2:3][N:4]([C:5](=[O:6])[c:7]1[cH:8][cH:9][c:10]2[n:16]1[CH2:15][c:14]1[c:13]([cH:20][cH:19][cH:18][cH:17]1)[N:12]([C:21](=[O:22])[c:23]1[cH:24][c:25]([CH3:39])[c:26](-[c:29]3[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]3)[cH:27][cH:28]1)[CH2:11]2)[CH3:40])[CH2:41][OH:42]>>[O:1]1[CH:2]([CH2:3][N:4]([C:5](=[O:6])[c:7]2[cH:8][cH:9][c:10]3[n:16]2[CH2:15][c:14]2[c:13]([cH:20][cH:19][cH:18][cH:17]2)[N:12]([C:21](=[O:22])[c:23]2[cH:24][c:25]([CH3:39])[c:26](-[c:29]4[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]4)[cH:27][cH:28]2)[CH2:11]3)[CH3:40])[CH2:41][O:42][C:52]1=[O:53]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e39442cc6e7346e794f48e45467e94c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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