Methanol → 5-acetamido-1H-indole-2-carboxylic Acid

HRID 2347321Notes

Reaction equation

HRID 2347321 reaction equation
[C:3]([CH3:4])(=[O:5])[NH:6][c:7]1[cH:8][c:9]2[cH:10][c:11]([C:25](=[O:26])[O-:27])[n:12]([C:16]([O:17][CH2:18][CH2:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[c:13]2[cH:14][cH:15]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:28][OH:29].[Li+:1].[OH-:2]>>[C:3]([CH3:4])(=[O:5])[NH:6][c:7]1[cH:8][c:9]2[cH:10][c:11]([C:25](=[O:26])[OH:27])[nH:12][c:13]2[cH:14][cH:15]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 867616451-(1,1-dimethylethyl)2-ethyl 5-(acetylamino)-1H-indole-1,2-dicarboxylate

Product 1

HCID 107751705-acetamido-1H-indole-2-carboxylic Acid

Sources & evidence

ORD record
ord-1d06f1e8a74740fe91923d17f688f34d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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