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HRID234747

反应详情

EQUATION

反应方程式

HRID 234747 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：c1ccc(C(NC2C3CC4CC(C3)CC2(OCc2ccc(-c3nc5ccccc5o3)cc2)C4)(c2ccccc2)c2ccccc2)cc1
HCID54303745

未命名化合物

PRODUCTS

生成物

1
结构：Cl.NC1C2CC3CC(C2)CC1(OCc1ccc(-c2nc4ccccc4o2)cc1)C3
HCID86750229

未命名化合物

PROCEDURE

实验过程

N-trityl-1-[4-(benzoxazol-2-yl)benzyloxy]tricyclo[3.3.1.13,7 ]-decan-2-amine (0.88 g; 0.0014 mole) is combined with ethanolic HCl (20 ml). After 2 hours, TLC indicates the reaction is complete. The reaction mixture is evaporated to dryness and purified on a flash column, using 10% MeOH/CH2Cl2 to obtain 1-[4-(benzoxazol-2-yl)benzyloxy]-tricyclo[3.3.1.13,7 ]-decan-2-amine hydrochloride (m.p. 291°-293° C.).

WORKUP

后处理

  1. customThe reaction mixture is evaporated to dryness
  2. custompurified on a flash column