Hydrochloric Acid → Ethyl {3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl}acetate
Reaction equation
[Br:22][c:23]1[cH:24][c:25]([F:31])[c:26]([CH2:27][Br:28])[cH:29][cH:30]1.[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6](=[O:19])[nH:7][c:8](=[O:18])[n:9]([CH2:12][C:13](=[O:14])[O:15][CH2:16][CH3:17])[c:10]2[cH:11]1.[ClH:32].[H-:20].[Na+:21]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6](=[O:19])[n:7]([CH2:27][c:26]3[c:25]([F:31])[cH:24][c:23]([Br:22])[cH:30][cH:29]3)[c:8](=[O:18])[n:9]([CH2:12][C:13](=[O:14])[O:15][CH2:16][CH3:17])[c:10]2[cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-04b6ebd191f34e068b83b188e81b9ff4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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