Acetonitrile → 1-(5-Bromopyrimidin-2-yl)piperidin-4-ol
Reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([Cl:24])[n:22][cH:23]1.[CH3:25][C:26]#[N:27].[CH:8]([N:9]([CH:10]([CH3:11])[CH3:12])[CH2:13][CH3:14])([CH3:15])[CH3:16].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([c:21]2[n:20][cH:19][c:18]([Br:17])[cH:23][n:22]2)[CH2:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-04294ea00e434f8ba5aa4de379155399
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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