Bicarbonate Ion → 1-(2-Chloro-4-nitrobenzyl)-4-methylpiperazine

HRID 2348024Notes

Reaction equation

HRID 2348024 reaction equation
[Br:1][CH2:2][c:3]1[c:4]([Cl:12])[cH:5][c:6]([N+:9](=[O:10])[O-:11])[cH:7][cH:8]1.[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[CH3:20][N:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[Cl:32][CH2:33][Cl:34].[Na+:31].[O-:27][C:28]([OH:29])=[O:30]>>[CH2:2]([c:3]1[c:4]([Cl:12])[cH:5][c:6]([N+:9](=[O:10])[O-:11])[cH:7][cH:8]1)[N:24]1[CH2:23][CH2:22][N:21]([CH3:20])[CH2:26][CH2:25]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 8471TriethylamineHCID 531671-MethylpiperazineHCID 30163681-(Bromomethyl)-2-chloro-4-nitrobenzene

Product 1

HCID 667358141-(2-Chloro-4-nitrobenzyl)-4-methylpiperazine

Sources & evidence

ORD record
ord-342861842be5439ea7492c04da4b401c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…