Dichloromethane → 1-(Piperidin-1-yl)-4-(2-fluoro-5-bromobenzyloxy)butane
Reaction equation
[CH2:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1.[CH2:27]([Cl:28])[Cl:29].[F:1][c:2]1[c:3]([CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][Br:10])[cH:11][c:12]([Br:15])[cH:13][cH:14]1.[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[F:1][c:2]1[c:3]([CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][N:19]2[CH2:18][CH2:17][CH2:16][CH2:21][CH2:20]2)[cH:11][c:12]([Br:15])[cH:13][cH:14]1Participants
5
Sources & evidence
- ORD record
- ord-a99c8eb7815e40698a890f645e96f156
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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