2-Bromotoluene → (+/-)-4'-[1-(Dimethylamino)ethyl]-2-methylbiphenyl
Reaction equation
[Br:2][c:3]1[c:4]([CH3:9])[cH:5][cH:6][cH:7][cH:8]1.[CH3:10][N:11]([CH:12]([CH3:13])[c:14]1[cH:15][cH:16][c:17]([Br:20])[cH:18][cH:19]1)[CH3:21].[Mg:1].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1.[Pd:27].[c:28]1([PH:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[c:3]1(-[c:17]2[cH:16][cH:15][c:14]([CH:12]([N:11]([CH3:10])[CH3:21])[CH3:13])[cH:19][cH:18]2)[c:4]([CH3:9])[cH:5][cH:6][cH:7][cH:8]1Participants
7
Sources & evidence
- ORD record
- ord-4728232c75684b5a8b73b51386913e94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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