Diisopropylamine → 2-(3-Chloro-4-methylsulfanyl-phenyl)-3-(1,4-dioxa-spiro[4.5]dec-8-yl)-propionic acid methyl ester
Reaction equation
[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][O:14][C:15]([CH2:16][c:17]1[cH:18][c:19]([Cl:25])[c:20]([S:23][CH3:24])[cH:21][cH:22]1)=[O:26].[CH3:44][N:45]1[CH2:46][CH2:47][CH2:48][N:49]([CH3:50])[C:51]1=[O:52].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[I:27][CH2:28][CH:29]1[CH2:30][CH2:31][C:32]2([O:33][CH2:34][CH2:35][O:36]2)[CH2:37][CH2:38]1.[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH3:13][O:14][C:15]([CH:16]([c:17]1[cH:18][c:19]([Cl:25])[c:20]([S:23][CH3:24])[cH:21][cH:22]1)[CH2:28][CH:29]1[CH2:30][CH2:31][C:32]2([O:33][CH2:34][CH2:35][O:36]2)[CH2:37][CH2:38]1)=[O:26]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f316f66221a74d27810adc5f51f073f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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