1,2-Dichloroethane → 6-Amino-2-cyclopropyl-5-methylpyrimidine-4-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7][c:8]([CH:14]2[CH2:15][CH2:16]2)[n:9][c:10]([NH2:13])[c:11]1[Br:12].[CH3:17][Sn:18]([CH3:19])([CH3:20])[CH3:21].[Cl:22][CH2:23][CH2:24][Cl:25].[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7][c:8]([CH:14]2[CH2:15][CH2:16]2)[n:9][c:10]([NH2:13])[c:11]1[CH3:17]Participants
6
Sources & evidence
- ORD record
- ord-279df040ce8a4278af2689e9fd2f7834
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…