Dimethylformamide → 6-Isopropoxypicolinaldehyde

HRID 2349704Notes

Reaction equation

HRID 2349704 reaction equation
[Br:1][c:2]1[n:3][c:4]([O:8][CH:9]([CH3:10])[CH3:11])[cH:5][cH:6][cH:7]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[O:17]=[CH:18][N:19]([CH3:20])[CH3:21]>>[c:2]1([CH:18]=[O:17])[n:3][c:4]([O:8][CH:9]([CH3:10])[CH3:11])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 221807682-Bromo-6-isopropoxypyridineHCID 178418339Butyllithium

Product 1

HCID 450910446-Isopropoxypicolinaldehyde

Sources & evidence

ORD record
ord-4a8487c0bf7c40889e387b756aba2ef1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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