Tetrahydrofuran → 3-[1-(4-Bromo-2-methylphenyl)ethyl]-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one
Reaction equation
[Br:9][c:10]1[cH:11][c:12]([CH3:36])[c:13]([CH:16]([CH3:17])[N:18]2[C:19](=[O:35])[O:20][C:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)([CH2:30][C:31]3([CH3:34])[O:32][CH2:33]3)[CH2:22][CH2:23]2)[cH:14][cH:15]1.[CH2:1]([BH-:2]([CH2:3][CH3:4])[CH2:5][CH3:6])[CH3:7].[Li+:8].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[Br:9][c:10]1[cH:11][c:12]([CH3:36])[c:13]([CH:16]([CH3:17])[N:18]2[C:19](=[O:35])[O:20][C:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)([CH2:30][C:31]([OH:32])([CH3:33])[CH3:34])[CH2:22][CH2:23]2)[cH:14][cH:15]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-46b3cd2befb04bcd9d12a09409084d3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…