(1,2-Dibromoethyl)benzene → HCID 13112855, compound

HRID 2351291Notes

Reaction equation

HRID 2351291 reaction equation
Br[CH:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:3]Br.[SH:11][C:12]1[NH:13][C:14]2[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=2[N:16]=1>CN(C)C=O>[C:5]1([CH:2]2[S:11][C:12]3=[N:16][C:15]4[CH:17]=[CH:18][CH:19]=[CH:20][C:14]=4[N:13]3[CH2:3]2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 7145(1,2-Dibromoethyl)benzeneHCID 178527775HCID 178527775, compound

Product 1

HCID 13112855HCID 13112855, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

(1,2-Dibromoethyl)benzene (21 g) was treated with 2-mercaptobenzimidazole (17 g) in dimethylformamide (100 ml) and the mixture was heated at 100° C. for 36 hours. On cooling, the solid material was removed by filtration and recrystallised from methanol and ethyl acetate to give the title compound as the hydrobromide salt (13.68 g). mp 207°-210° C.

Workup

  1. temperatureOn cooling
  2. customthe solid material was removed by filtration
  3. customrecrystallised from methanol and ethyl acetate

Sources & evidence

ORD record
ord-cf51b49fd2f94f11bc5e1f8209cb88e4
Source dataset
uspto-grants-1989_10
Patent number
US04873237

Reaction notes

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