反应详情

Prepared analogously to Example 1 from 4-(chlorocarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one and (+)-2-[2-[(diethylamino)methyl]-piperidin-l-yl]ethanamine in a yield of 55% of theory. Colourless crystals, m.p. 131°-132° C. (acetonitrile); [α]D20 =-13.66° (dilute aqueous hydrochloric acid).