反应详情

Prepared analogously to Example 109 from 11-[[[2-bromo-ethyl]amino]carbonyl]-9-chloro-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[4-(diethylamino)butyl]piperidine, but using dimethylformamide instead of acetonitrile, in a yield of 19% of theory. Colourless crystals, m.p. 157° C.