反应详情

Benzene (50 cc), ethyl acetylacetate (30 g, 231 mmol) and ethylene glycol (16 g), followed by p-toluenesulphonic acid (0.5 g), are introduced into a round-bottomed flask fitted with a Dean and Stark apparatus. The mixture is heated under reflux while the azeotrope is distilled off for 2 hours 30 minutes. After the removal of benzene, ethyl 3,3-ethylenedioxybutanoate (37 g) is obtained (B.P.12 =98° C.).

1. additionare introduced into a round-bottomed flask
2. customfitted with a Dean and Stark apparatus
3. temperatureThe mixture is heated
4. temperatureunder reflux while the azeotrope
5. distillationis distilled off for 2 hours 30 minutes
6. customAfter the removal of benzene