Hydrochloric Acid → HCID 14819287, compound

HRID 2352395Notes

Reaction equation

HRID 2352395 reaction equation
C([O:5][C:6](=[O:16])[C@H:7]([CH3:15])[NH:8][CH:9]1[CH2:13][CH2:12][O:11][C:10]1=[O:14])(C)(C)C.[ClH:17]>C(OCC)(=O)C>[ClH:17].[O:14]=[C:10]1[CH:9]([NH:8][C@H:7]([C:6]([OH:16])=[O:5])[CH3:15])[CH2:13][CH2:12][O:11]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14819290HCID 14819290, compound

Product 1

HCID 14819287HCID 14819287, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

In 5 ml of an ethyl acetate solution saturated with hydrochloric acid, 1.66 g of N-(2-oxo-3-tetrahydrofuranyl)-L-alanine t-butyl ester was dissolved. The resultant solution was stirred for 3 hours at room temperature. Crystals which had precipitated were collected by filtration. After washing the crystals with ethyl acetate and then with ether, they were dried to obtain 1.31 g of N-(2-oxo-3-tetrahydrofuranyl)-L-alanine hydrochloride as colorless crystals.

Workup

  1. customCrystals which had precipitated
  2. filtrationwere collected by filtration
  3. washAfter washing the crystals with ethyl acetate
  4. dry with materialwith ether, they were dried

Sources & evidence

ORD record
ord-ebe8ec37063d44b0b0c88177aebc4df2
Source dataset
uspto-grants-1989_10
Patent number
US04876359

Reaction notes

Loading…