Triethylamine → 2-(2-Oxooxazolidin-3-yl)ethyl methanesulfonate

HRID 2353496Notes

Reaction equation

HRID 2353496 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][O:6][C:5]1=[O:9].C(N(CC)CC)C.[CH3:17][S:18](Cl)(=[O:20])=[O:19]>C1COCC1>[CH3:17][S:18]([O:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][O:6][C:5]1=[O:9])(=[O:20])=[O:19]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 768872-Oxazolidinone, 3-(2-hydroxyethyl)-

Product 1

HCID 446271152-(2-Oxooxazolidin-3-yl)ethyl methanesulfonate

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The 3-(2-hydroxyethyl)-2-oxazolidinone (Frinton Laboratories, 0.16 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound which was used directly in the next reaction.

Sources & evidence

ORD record
ord-04b27b2ed2cd4e5da2490e0e05dd4565
Source dataset
uspto-grants-2010_07
Patent number
US07750039B2

Reaction notes

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