反应详情

温度

80 °C

2,6-Dimethyl-pyridin-4-ylamine (1.22 g, 10 mmol) is dissolved in dry dioxane (30 mL) and CDI (891 mg, 5.5 mmol) is added. The mixture is heated at 80° C. for 1 h. Further CDI (160 mg) is added and stirring is continued for 15 h. The mixture is evaporated and purified by FC (SiO2, EtOAc-MeOH) to provide the title compound.

1. customThe mixture is evaporated
2. custompurified by FC (SiO2, EtOAc-MeOH)