反应详情

温度

50 °C

Add 4N hydrogen chloride in 1,4-dioxane (25 mL) to a solution of (4-hydroxymethyl-benzyl)-carbamic acid tert-butyl ester (3.0 g, 12.6 mmol) in 1,4-dioxane (25 mL). Heat the reaction mixture at 50° C. for 1 hr. Filter the solid and wash it with ethyl acetate to give the title compound (2.1 g, 12.1 mmol).

1. filtrationFilter the solid
2. washwash it with ethyl acetate