Water → HCID 53649348, compound

HRID 2356670Notes

Reaction equation

HRID 2356670 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.CO[CH:14](OC)[N:15]([CH3:17])[CH3:16].O>CN(C)C=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([N:11]=[CH:14][N:15]([CH3:17])[CH3:16])(=[O:9])=[O:10])=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 962WaterHCID 696964-BromobenzenesulfonamideHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 53649348HCID 53649348, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

0.325 g of 4-bromobenzenesulfonamide was admixed with 0.82 g of dimethylformamide dimethyl acetal in 1.6 ml of dry dimethylformamide and stirred at room temperature for 90 min. For workup, the reaction mixture was admixed with 10 ml of water, and the precipitate was filtered off with suction, filtered and dried under reduced pressure. 4-Bromo-N-[1-dimethylaminomethylidene]benzenesulfonamide was obtained in a yield of 85%. Molecular weight 289.97 (C9H11BrN2O2S); retention time Rt=1.3 min. [B]; MS (ESI): 290.96 (MH+).

Workup

  1. filtrationthe precipitate was filtered off with suction
  2. filtrationfiltered
  3. customdried under reduced pressure

Sources & evidence

ORD record
ord-c1a0771bee634503b16d985923cd08ce
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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