Water → HCID 68677827, compound

HRID 2356671Notes

Reaction equation

HRID 2356671 reaction equation
[F:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].CO[CH:14](OC)[N:15]([CH3:17])[CH3:16].O>CN(C)C=O>[F:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[N:4]=[CH:14][N:15]([CH3:17])[CH3:16]

Participants

5

Reactant 3

HCID 962WaterHCID 78373Dimethylformamide dimethyl acetalHCID 1012542-Fluoro-4-nitroaniline

Product 1

HCID 68677827HCID 68677827, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

5 g of 2-fluoro-4-nitroaniline were dissolved in 35 ml of dry dimethylformamide, admixed at room temperature with 19.90 g of dimethylformamide dimethyl acetal and stirred for 90 min. For workup, 250 ml of water were added to the reaction mixture, and the precipitate was filtered off with suction, washed with water and dried. N′-(2-Fluoro-4-nitrophenyl)-N,N-dimethylformamidine was obtained in a yield of 85%. Molecular weight 211.07 (C9H10FN3O2); retention time Rt=0.49 min. [B]; MS (ESI):

Workup

  1. filtrationthe precipitate was filtered off with suction
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-996fd36099b741fc85c79c18fa5d95d8
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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