Sodium Bicarbonate → HCID 277395, compound

HRID 2357421Notes

Reaction equation

HRID 2357421 reaction equation
[C:1]1([C:7](=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([O:19][CH3:20])[CH:13]=2)C(O)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O-])(O)=O.[Na+]>>[OH:18][C:15]1[CH:16]=[CH:17][C:12]([CH:11]=[CH:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[CH:13][C:14]=1[O:19][CH3:20]

Participants

3

Reactant 2

HCID 516892Sodium BicarbonateHCID 53411296α-[(4-Hydroxy-3-methoxyphenyl)methylene]benzeneacetic acid

Product 1

HCID 277395HCID 277395, compoundYield 72%

Procedure

A mixture of α-phenyl-4-hydroxy-3-methoxy cinnamic acid (0.0083 mol), NaHCO3 (10%, 5 mL) and polyethylene glycol (5 mL) were taken in a 100 ml round bottom flask fitted with a condenser. The flask was shaken well and placed inside the microwave oven and irradiated (200 W, 180° C.) for 10 minutes in parts. After completion of reaction, the reaction mixture was worked (yield 72%) as in example I. Spectral data as given in example I.

Workup

  1. customwere taken in a 100 ml round bottom flask
  2. customfitted with a condenser
  3. customirradiated (200 W, 180° C.) for 10 minutes in parts
  4. customAfter completion of reaction

Sources & evidence

ORD record
ord-d5e4ef01530649c48224917d5dfd92e5
Source dataset
uspto-grants-2010_07
Patent number
US07759527B2

Reaction notes

Loading…