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HRID2357683

反应详情

EQUATION

反应方程式

HRID 2357683 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：Cl.FC(F)(F)c1nnc2n1CCNC2
HCID11961371

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine--hydrogen chloride (1/1)

C6H8ClF3N4

结构：Clc1ccc2c(Cl)nncc2c1
HCID14322333

1,6-Dichlorophthalazine

C8H4Cl2N2

PRODUCTS

生成物

1
结构：FC(F)(F)c1nnc2n1CCN(c1nncc3cc(Cl)ccc13)C2
HCID68453553

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN1CCCC1=O
溶剂HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

PROCEDURE

实验过程

The title compound was prepared according to the method described in Example 19, using 1,6-dichlorophthalazine (400 mg, 2010 μmol), 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride (Balsells, et. al. Org. Lett., 7:1039-1042 (2005), 689 mg, 3015 μmol) and N,N-diisopropylethylamine (702 μl, 4019 μmol) in NMP (5 mL). MS (ESI, pos. ion) m/z: 355 (M+1).